Study of Dental Caries and PTH Gene

نویسندگان

چکیده

Parathyroid hormone (PTH) is essential for calcium and phosphate homeostasis in odontogenesis-related cells. Therefore, the present study aimed to investigate association between single nucleotide polymorphisms gene encoding PTH, dental caries Brazilian children. Three hundred fifty-three children (170 boys 183 girls, age ranging from 8 11 years old) were included this study. The International System Detection Assessment of Carious Lesions (ICDAS) was used diagnosis caries. Visible biofilm also evaluated during clinical examination. Genomic DNA extracted saliva real-time PCR evaluate rs6256, rs307247 rs694 PTH gene. Dental classified ICDAS 0 vs. 1?6 or 1?2 3?6 . Chi-square test, binary logistic regression adjusted by haplotype analyses performed ( p < 0.05). Biofilm associated with (p There no associations rs307247, none > In conclusion, supports that PTH-encoding are not

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ژورنال

عنوان ژورنال: Frontiers in dental medicine

سال: 2021

ISSN: ['2673-4915']

DOI: https://doi.org/10.3389/fdmed.2021.703549