Study of Dental Caries and PTH Gene
نویسندگان
چکیده
Parathyroid hormone (PTH) is essential for calcium and phosphate homeostasis in odontogenesis-related cells. Therefore, the present study aimed to investigate association between single nucleotide polymorphisms gene encoding PTH, dental caries Brazilian children. Three hundred fifty-three children (170 boys 183 girls, age ranging from 8 11 years old) were included this study. The International System Detection Assessment of Carious Lesions (ICDAS) was used diagnosis caries. Visible biofilm also evaluated during clinical examination. Genomic DNA extracted saliva real-time PCR evaluate rs6256, rs307247 rs694 PTH gene. Dental classified ICDAS 0 vs. 1?6 or 1?2 3?6 . Chi-square test, binary logistic regression adjusted by haplotype analyses performed ( p < 0.05). Biofilm associated with (p There no associations rs307247, none > In conclusion, supports that PTH-encoding are not
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Dental caries is one of the most prevalent diseases afflicting mankind. It reached a peak in the 1950s but has been declining drastically in recent years in children and young adults. This article describes the three contributing factors in dental caries: microbial plaque, tooth susceptibility, and diet, and discusses practical preventive measures which help to reduce caries incidence. Some of ...
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ژورنال
عنوان ژورنال: Frontiers in dental medicine
سال: 2021
ISSN: ['2673-4915']
DOI: https://doi.org/10.3389/fdmed.2021.703549